FREEZE-THAW-INDUCED AGGREGATION OF BOVINE GAMMA GLOBULIN WAS EFFICIENTLY INHIBITED BY AN INTRINSICALLY DISORDERED PLANT PROTEIN DEHYDRIN

Freeze-thaw-induced aggregation of bovine gamma globulin was efficiently inhibited by an intrinsically disordered plant protein dehydrin

Immunoglobulin, which is widely used in the formulation of protein drugs, is prone to aggregation due to freezing.The aggregated immunoglobulin exhibits decreased immune-reactivity and increasing immunogenicity.Accordingly, large amounts of excipients are added to immunoglobulin drugs to prevent aggregation.In the present study, we found that an Ar

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Reproductive Biology of Varronia curassavica Jacq. (Boraginaceae)

ABSTRACT Varronia curassavica, a subshrubby medicinal species associated with restinga in the Atlantic Forest, has been exploited by local people and the pharmaceutical industry.Indeed, restingas have experienced a continuous process of degradation, and thus, with species and ecosystem both at risk, efforts to support conservation actions are requi

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Innovative Strategies and Approaches to Adapting Ukrainian Business Models and Quality Management in Conditions of Uncertainty

During the war, Ukrainian business models underwent strategic changes, adapting to the conditions of uncertainty and high levels of riskiness, which included cost optimization, new logistics flows, hybrid work format, energy savings, safety-oriented management, transformation of quality management and the introduction of innovations to remain compe

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